Prenatal induction of sucrase activity in rat jejunum.
نویسندگان
چکیده
Daily application of cortisone acetate (10mg/100g body wt.) or L-tri-iodothyronine (20 microng/100g body wt.) to female rats in the last (third) week of pregnancy elicits a precocious appearance of jejunal sucrase in their foetuses.
منابع مشابه
Induction of histone acetylation on the sucrase-isomaltase gene in the postnatal rat jejunum.
The rapid induction of the sucrase-isomaltase (SI) gene in rat jejunum from the onset to final period of weaning was associated with increases of the acetylation of histones H3 and H4 on the promoter/transcriptional region of the gene, suggesting that an abrupt jejunal induction of histone acetylation changes on the SI gene during this period may be concerned with the expression of the gene.
متن کاملMucosal function in rat jejunum and ileum is altered by induction of colitis.
Many studies dealing with trinitrobenzene sulfonic acid (TNBS) colitis in rats have been carried out referring only to the colon. In humans, ulcerative colitis (UC) can extend a variable distance into the terminal ileum in a phenomenon known as backwash ileitis (BWI). The aim of this study was therefore to examine the effect of TNBS-induced colitis on different aspects of the rat ileum and jeju...
متن کاملDeterminants of regional sucrase-isomaltase expression in adult rat small intestine.
Sucrase-isomaltase (SI) expression along the longitudinal and vertical axis of the small intestine was studied by sequentially isolating enterocytes from villus to crypt of rat proximal jejunum and distal ileum. Gradients of sucrase activity were observed with greatest activity occurring in jejunal and villus regions. Along the villus-to-crypt axis, gradients of SI mRNA abundance corresponded w...
متن کاملDegradation of sucrase-isomaltase in the ileum of jejunum-bypassed rats.
At 3 weeks after jejunal-bypass operation in the rat, the proximal ileum exhibited a greater sucrase specific activity than did sham-operated controls, whereas isomaltase activity was unaffected. Electroimmunoassay of sucrase-isomaltase and a degradation product, isomaltase monomer, revealed an elevated molar ratio of sucrase subunit to isomaltase subunit in operated rats, suggesting a decrease...
متن کاملCell migration and cortisone induction of sucrase activity in jejunum and ileum.
The increase of sucrase activity in homogenates of jejunum and ileum of suckling rats after cortisone administration has been investigated. Serial tissue sections of villi and crypts were also assayed for sucrase activity and these results were compared with the migration of cells labelled with [(3)H]thymidine along the villus. By using a low dose of cortisone (0.5mg/day per 100g body wt.) it w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Biochemical journal
دوره 162 2 شماره
صفحات -
تاریخ انتشار 1977